⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL679998 | 0.62 | CYP2A6 (0.43) | — | |
| SCHEMBL549035 | 0.60 | — | — | |
| SCHEMBL2900102 | 0.57 | CYP19A1 (0.36) | — | |
| SCHEMBL128316 | 0.48 | — | — | |
| SCHEMBL499859 | 0.48 | — | — | |
| SCHEMBL3626662 | 0.45 | — | — | |
| SCHEMBL12020220 | 0.42 | — | — | |
| SCHEMBL7009257 | 0.40 | — | — | |
| SCHEMBL12703772 | 0.40 | — | — | |
| SCHEMBL14401341 | 0.40 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2991 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024115549-A1 | ARYL- AND HETEROARYL-SULFONAMIDE DERIVATIVES AS CCR8 MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-06-06 | — | — | WO | claimed |
| US-20240124474-A1 | HER2 MUTATION INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2024-04-18 | — | — | US | claimed |
| US-11780858-B2 | Pyridinamine-pyridone and pyrimidinamine-pyridone compounds | SPRINT BIOSCIENCE AB (SE) | 2023-10-10 | — | — | US | claimed |
| EP-4236942-A1 | ISOXAZOLE DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | Arena Pharmaceuticals, Inc. (US) | 2023-09-06 | — | — | EP | claimed |
| EP-4236937-A1 | PYRIMIDINE DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | Arena Pharmaceuticals, Inc. (US) | 2023-09-06 | — | — | EP | claimed |
| CN-113861203-B | 4-aromatic alkynyl substituted 7H-pyrrolo [2,3-d ] pyrimidine amide compound and preparation method and application thereof | 安徽大学 | 2023-08-08 | — | — | CN | claimed |
| US-11667644-B2 | Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-06-06 | — | — | US | claimed |
| US-20230136796-A1 | Tripeptide Propylene Oxide Derivative and Preparation Method and Application thereof | SHENZHEN JIKANG PHARMACEUTICAL TECHNOLOGY CO., LTD (CN) | 2023-05-04 | — | — | US | claimed |
| EP-4169581-A1 | PYRIDINAMINE-PYRIDONE AND PYRIMIDINAMINE-PYRIDONE COMPOUNDS | Sprint Bioscience AB (SE) | 2023-04-26 | — | — | EP | claimed |
| US-20230096602-A1 | TETRAHYDROCYCLOPENTA[B]INDOLE COMPOUNDS FOR TREATMENT OF RENAL DISEASE | EIRGEN PHARMA LTD. (IE) | 2023-03-30 | — | — | US | claimed |
| EP-0074229-A1 | Triazole gastric anti-secretory agents | PFIZER INC. (US) | 1983-03-16 | — | — | EP | claimed |
| EP-0061094-A1 | Electrophotographic recording material | BASF Aktiengesellschaft (DE) | 1982-09-29 | — | — | EP | claimed |
| EP-0061091-A1 | Electrophotographic recording material | BASF Aktiengesellschaft (DE) | 1982-09-29 | — | — | EP | claimed |
| US-4282028-A | Herbicidal and plant-growth-regulating N-substituted-N-(2,5-dialkylpyrrol-1-yl) haloacetamides | CHEVRON RESEARCH COMPANY (US) | 1981-08-04 | — | — | US | claimed |
| EP-0018674-A1 | Benzodioxincarboxylic acid derivatives, their preparation and their inclusion in lipogenesis inhibiting compositions | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1980-11-12 | — | — | EP | claimed |
| US-4205076-A | Lipogenesis inhibition by certain esters of substituted benzodioxincarboxylic acids | SHELL OIL COMPANY (US) | 1980-05-27 | — | — | US | claimed |
| US-4205079-A | LIPORENESIS INHIBITORS | SHELL OIL COMPANY (US) | 1980-05-27 | — | — | US | claimed |
| US-4202818-A | Lipogenesis inhibition by certain esters of substituted benzodioxincarboxylic acids | SHELL OIL COMPANY (US) | 1980-05-13 | — | — | US | claimed |
| US-3979404-A | FUNGICIDES | SYNTEX (U.S.A.) INC. (US) | 1976-09-07 | — | — | US | claimed |
| US-3946031-A | FUNGICIDES | SYNTEX INC. (US) | 1976-03-23 | — | — | US | claimed |