Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | CCR1 | P32246 | 5/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4692561 | 0.88 | LMNA (0.56) | CHRM2CHRM1CHRM3CCR1LMNA | |
| SCHEMBL4692563 | 0.88 | LMNA (0.56) | CHRM2CHRM1CHRM3CCR1LMNA | |
| SCHEMBL4688359 | 0.75 | CHRM2 (0.56) | CHRM2CHRM1CHRM3CCR1HDAC3 | |
| SCHEMBL4688362 | 0.75 | CHRM2 (0.56) | CHRM2CHRM1CHRM3CCR1HDAC3 | |
| SCHEMBL24501858 | 0.74 | TEAD1 (0.63) | FAAHHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL22731708 | 0.74 | TEAD1 (0.63) | FAAHHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL22731845 | 0.74 | TEAD1 (0.63) | FAAHHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4686638 | 0.73 | LMNA (0.60) | CHRM2CHRM1CHRM3CCR1LMNA | |
| SCHEMBL4687584 | 0.73 | LMNA (0.60) | CHRM2CHRM1CHRM3CCR1LMNA | |
| SCHEMBL4685919 | 0.73 | CCR1 (0.48) | CHRM2CHRM1CHRM3CCR1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590345-A1 | XANTHINE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES, LTD. (IN) | 2005-11-02 | — | — | EP | claimed |
| WO-2004056810-A1 | XANTHINE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2004-07-08 | — | — | WO | claimed |
| EP-1590345-A1 | XANTHINE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES, LTD. (IN) | 2005-11-02 | — | — | EP | disclosed |
| WO-2004056810-A1 | XANTHINE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2004-07-08 | — | — | WO | disclosed |