Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 14/20 | 0.61 |
| ▸ | ACACA | Q13085 | 14/20 | 0.61 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.43 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.42 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6185259 | 0.89 | ACACB (0.56) | ACACBACACABCHEKDM2B | |
| SCHEMBL6182987 | 0.88 | ACACB (0.73) | ACACBACACABCHE | |
| SCHEMBL978121 | 0.84 | ACACB (0.77) | ACACBACACAKDM2B | |
| SCHEMBL2622329 | 0.84 | ACACB (0.77) | ACACBACACAKDM2B | |
| SCHEMBL6183887 | 0.81 | ACACB (0.57) | ACACBACACABCHEL3MBTL3L3MBTL1 | |
| SCHEMBL6184619 | 0.80 | ACACB (0.70) | ACACBACACAKDM2BL3MBTL3L3MBTL1 | |
| SCHEMBL6183884 | 0.80 | ACACB (0.70) | ACACBACACAKDM2B | |
| SCHEMBL6183602 | 0.80 | ACACB (0.67) | ACACBACACAKDM2BL3MBTL1 | |
| SCHEMBL3465253 | 0.80 | ACACB (0.74) | ACACBACACAKDM2BL3MBTL3L3MBTL1 | |
| SCHEMBL6183390 | 0.80 | ACACB (0.74) | ACACBACACAKDM2BL3MBTL3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478437-B1 | ACC INHIBITORS | PFIZER PROD INC (US) | 2005-08-31 | — | — | EP | claimed |