Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 15/20 | 0.56 |
| ▸ | ACACA | Q13085 | 15/20 | 0.56 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6184795 | 0.89 | ACACB (0.61) | ACACBACACAKDM2BBCHE | |
| SCHEMBL975322 | 0.86 | ACACB (0.69) | ACACBACACAKDM2B | |
| SCHEMBL6182987 | 0.83 | ACACB (0.73) | ACACBACACABCHE | |
| SCHEMBL6183887 | 0.79 | ACACB (0.57) | ACACBACACABCHE | |
| SCHEMBL978121 | 0.78 | ACACB (0.77) | ACACBACACAKDM2B | |
| SCHEMBL2622329 | 0.78 | ACACB (0.77) | ACACBACACAKDM2B | |
| SCHEMBL6182583 | 0.77 | ACACB (0.75) | ACACBACACAKDM2B | |
| SCHEMBL6186970 | 0.76 | ACACB (0.54) | ACACBACACAKDM2BBCHE | |
| SCHEMBL6184619 | 0.76 | ACACB (0.70) | ACACBACACAKDM2B | |
| SCHEMBL976641 | 0.76 | ACACB (0.79) | ACACBACACAKDM2BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478437-B1 | ACC INHIBITORS | PFIZER PROD INC (US) | 2005-08-31 | — | — | EP | claimed |