Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 6/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6184164 | 0.94 | TBXA2R (0.58) | TBXAS1TBXA2R | |
| SCHEMBL6182528 | 0.91 | TBXA2R (0.57) | TBXAS1TBXA2R | |
| SCHEMBL7227176 | 0.90 | TBXA2R (0.57) | ALDH1A1MAPTTBXAS1TBXA2R | |
| SCHEMBL6186223 | 0.89 | TBXA2R (0.59) | TBXAS1TBXA2R | |
| Hydrochloric Acid SCHEMBL7227614 | 0.87 | TBXA2R (0.56) | ALDH1A1MAPTTBXAS1TBXA2RHRH1 | |
| SCHEMBL7235498 | 0.84 | TBXA2R (0.59) | ALDH1A1MAPTTBXAS1TBXA2R | |
| SCHEMBL6185574 | 0.82 | HRH1 (0.52) | HRH1 | |
| SCHEMBL6184568 | 0.82 | TBXA2R (0.54) | ALDH1A1TBXA2R | |
| SCHEMBL6184510 | 0.79 | KDM4E (0.50) | HRH1 | |
| SCHEMBL7225547 | 0.79 | TBXA2R (0.60) | ALDH1A1MAPTTBXAS1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1275641-B1 | Benzenesulfonamide derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2005-01-12 | — | — | EP | disclosed |
| US-6541471-B1 | Useful as a TXA2 receptor antagonist and a 5-HT2 receptor antagonist | LES LABORATOIRES SERVIER (FR) | 2003-04-01 | — | — | US | disclosed |
| EP-1275641-A2 | Benzenesulfonamide derivatives, process for their preparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2003-01-15 | — | — | EP | disclosed |