Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6184164 | 0.89 | TBXA2R (0.58) | TBXA2R | |
| SCHEMBL6182528 | 0.87 | TBXA2R (0.57) | TBXA2R | |
| SCHEMBL7227176 | 0.85 | TBXA2R (0.57) | TBXA2RALDH1A1 | |
| SCHEMBL6186223 | 0.85 | TBXA2R (0.59) | TBXA2R | |
| Hydrochloric Acid SCHEMBL7227614 | 0.83 | TBXA2R (0.56) | TBXA2RALDH1A1 | |
| SCHEMBL6184959 | 0.82 | ALDH1A1 (0.50) | TBXA2RALDH1A1 | |
| SCHEMBL7235498 | 0.79 | TBXA2R (0.59) | TBXA2RALDH1A1 | |
| SCHEMBL11254742 | 0.79 | HRH1 (0.59) | PRMT1 | |
| SCHEMBL11260485 | 0.78 | HRH1 (0.59) | — | |
| SCHEMBL6187752 | 0.77 | ABCB1 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1275641-B1 | Benzenesulfonamide derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2005-01-12 | — | — | EP | claimed |