⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2001727 | 0.70 | — | — | |
| SCHEMBL348778 | 0.65 | — | — | |
| SCHEMBL31295070 | 0.64 | — | — | |
| SCHEMBL1009286 | 0.64 | — | — | |
| SCHEMBL13518555 | 0.64 | — | — | |
| SCHEMBL8594212 | 0.63 | HRH3 (0.38) | — | |
| SCHEMBL3782579 | 0.60 | — | — | |
| SCHEMBL10653768 | 0.59 | — | — | |
| SCHEMBL6723218 | 0.59 | — | — | |
| SCHEMBL5784468 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562599-B1 | Condensed thiadiazole derivative, method of its production, and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-09-04 | — | — | EP | claimed |
| US-6414003-B1 | ANTIULCER AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-07-02 | — | — | US | claimed |
| EP-0363223-A2 | 3-Aryloxymethyl-cephalosporin derivatives, their preparation and their medical use | Sankyo Company Limited (JP) | 1990-04-11 | — | — | EP | claimed |
| EP-1544197-A1 | Intermediates for cephem compounds | SHIONOGI & CO., LTD. (JP) | 2005-06-22 | — | — | EP | disclosed |
| EP-0614664-B2 | Quinolonecarboxylic acid derivatives, their preparation and their use as cell adhesion inhibitors | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-6458950-B1 | Compounds and pharmaceutical compositions containing the same | SHIONOGI & CO., LTD. (JP) | 2002-10-01 | — | — | US | disclosed |
| EP-0562599-B1 | Condensed thiadiazole derivative, method of its production, and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-09-04 | — | — | EP | disclosed |
| US-6414003-B1 | ANTIULCER AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-07-02 | — | — | US | disclosed |
| US-6214818-B1 | ANTIBIOTIC CEPHALOSPORINS | SHIONOGI & CO., LTD. (JP) | 2001-04-10 | — | — | US | disclosed |
| US-6169102-B1 | ANTI-HELICOBACTER PYLORI AGENT COMPRISING AN OXAZOLIN-4-ONE DERIVATIVE USEFUL AS A THERAPEUTIC AGENT FOR GASTRIC AND DUODENAL ULCER | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-02 | — | — | US | disclosed |
| US-6162828-A | IMMUNOLOGY; ANTIINFLAMMATORY AGENTS; ANTITUMOR AGENTS; BONE DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-12-19 | — | — | US | disclosed |
| US-4675399-A | N-HYDROXY-2-AZETIDINONES; ACYLATION, SOLVOLYSIS | NOTRE DAME UNIVERSITY (US) | 1987-06-23 | — | — | US | disclosed |
| EP-0225634-A2 | Antibacterial compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-06-16 | — | — | EP | disclosed |
| US-4665065-A | 3-pyrazolo(1,5-aαpyridinium cephem compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-05-12 | — | — | US | disclosed |
| EP-0216385-A2 | Antibacterial compounds | Takeda Chemical Industries, Ltd. (JP) | 1987-04-01 | — | — | EP | disclosed |
| US-4565654-A | BETA-LACTAMASE ENZYME INHIBITORS | UNIVERSITY OF NOTRE DAME DU LAC (US) | 1986-01-21 | — | — | US | disclosed |
| EP-0164113-A2 | 3-pyrazolo(1,5-a)pyridinium cephem compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1985-12-11 | — | — | EP | disclosed |
| EP-0164122-A2 | Cephem compounds | Takeda Chemical Industries, Ltd. (JP) | 1985-12-11 | — | — | EP | disclosed |
| EP-0160252-A2 | Antibacterial compounds | Takeda Chemical Industries, Ltd. (JP) | 1985-11-06 | — | — | EP | disclosed |
| EP-0123442-A1 | Improvements in or relating to a process for producing beta-lactam compounds | THE UNIVERSITY OF NOTRE DAME DU LAC (US) | 1984-10-31 | — | — | EP | disclosed |