Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 19/20 | 0.71 |
| ▸ | EGFR | P00533 | 3/20 | 0.59 |
| ▸ | GAK | O14976 | 1/20 | 0.59 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6186132 | 0.85 | SRC (0.59) | SRCEGFRERBB2 | |
| SCHEMBL6186103 | 0.84 | SRC (0.70) | SRC | |
| SCHEMBL6381073 | 0.83 | EGFR (0.69) | SRCEGFRGAKERBB2 | |
| SCHEMBL6184514 | 0.82 | SRC (1.00) | SRCEGFRGAKERBB2 | |
| SCHEMBL6188022 | 0.82 | SRC (0.49) | SRCEGFRERBB2 | |
| SCHEMBL6184586 | 0.82 | SRC (0.52) | SRCEGFRERBB2 | |
| SCHEMBL6185291 | 0.82 | SRC (0.70) | SRC | |
| SCHEMBL6184673 | 0.81 | SRC (0.60) | SRC | |
| SCHEMBL5257386 | 0.81 | SRC (0.68) | SRCEGFRGAK | |
| SCHEMBL6381064 | 0.81 | EGFR (0.72) | SRCEGFRGAKERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499594-B1 | PROCESS FOR THE PREPARATION OF 7-SUBSTITUTED-3-QUINOLINE AND 3-QUINOL-4-ONE CARBONITRILES | WYETH CORP (US) | 2005-08-17 | — | — | EP | claimed |