Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 12/20 | 0.49 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | ABL2 | P42684 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 3/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6186132 | 0.90 | SRC (0.59) | SRCABL1ABL2EGFRERBB2 | |
| SCHEMBL6184586 | 0.86 | SRC (0.52) | SRCABL1ABL2EGFRERBB2 | |
| SCHEMBL6185291 | 0.84 | SRC (0.70) | SRCPRKCQABL1ABL2 | |
| SCHEMBL6187804 | 0.83 | SRC (0.62) | SRCPRKCQABL1ABL2 | |
| SCHEMBL6183312 | 0.83 | SRC (0.73) | SRCPRKCQABL1ABL2EGFR | |
| SCHEMBL6185071 | 0.82 | SRC (0.71) | SRCEGFRERBB2 | |
| SCHEMBL6186103 | 0.82 | SRC (0.70) | SRCABL1 | |
| SCHEMBL6185380 | 0.82 | SRC (0.72) | SRCABL1ABL2EGFRERBB2 | |
| SCHEMBL6184673 | 0.81 | SRC (0.60) | SRCABL1ABL2 | |
| SCHEMBL6384502 | 0.81 | SRC (0.53) | SRCPRKCQABL1ABL2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499594-B1 | PROCESS FOR THE PREPARATION OF 7-SUBSTITUTED-3-QUINOLINE AND 3-QUINOL-4-ONE CARBONITRILES | WYETH CORP (US) | 2005-08-17 | — | — | EP | claimed |