Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 3/20 | 0.46 |
| ▸ | MME | P08473 | 6/20 | 0.45 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 5/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | GNPAT | O15228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6315187 | 0.86 | TGFBR1 (0.54) | TGFBR1MMEFNTAFNTBCA2 | |
| SCHEMBL4812250 | 0.86 | TGFBR1 (0.54) | TGFBR1MMEFNTAFNTBCA2 | |
| SCHEMBL4082387 | 0.83 | TGFBR1 (0.48) | TGFBR1MMEFNTAFNTBCA2 | |
| SCHEMBL31488806 | 0.83 | TGFBR1 (0.48) | TGFBR1MMEFNTAFNTBCA2 | |
| SCHEMBL8542259 | 0.83 | TGFBR1 (0.48) | TGFBR1MMEFNTAFNTBCA2 | |
| SCHEMBL1229828 | 0.81 | TGFBR1 (0.47) | TGFBR1MMEFNTAFNTBCA2 | |
| SCHEMBL31651029 | 0.81 | TGFBR1 (0.47) | TGFBR1MMEFNTAFNTBCA2 | |
| SCHEMBL29385234 | 0.81 | TGFBR1 (0.47) | TGFBR1MMEFNTAFNTBCA2 | |
| SCHEMBL19283433 | 0.81 | TGFBR1 (0.47) | TGFBR1MMEFNTAFNTBCA2 | |
| SCHEMBL455811 | 0.81 | TGFBR1 (0.47) | TGFBR1MMEFNTAFNTBCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521742-A1 | DIPHENYLAZETIDINONE DERIVATIVES FOR TREATING DISORDERS OF THE LIPID METABOLISM | AstraZeneca AB (SE) | 2005-04-13 | — | — | EP | disclosed |
| WO-2004005247-A1 | DIPHENYLAZETIDINONE DERIVATIVES FOR TREATING DISORDERS OF THE LIPID METABOLISM | ASTRAZENECA AB (SE) | 2004-01-15 | — | — | WO | disclosed |