Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 8/20 | 0.54 |
| ▸ | CCKBR | P32239 | 4/20 | 0.46 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.43 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6185910 | 1.00 | RIPK1 (0.54) | RIPK1CCKBRAGTR2HTRA1LMNA | |
| SCHEMBL25363009 | 0.82 | AKR1C3 (0.47) | AGTR2AKR1C3AKR1C1 | |
| SCHEMBL6695511 | 0.82 | AKR1C3 (0.47) | AGTR2AKR1C3AKR1C1 | |
| SCHEMBL9543379 | 0.81 | HTRA1 (0.60) | HTRA1 | |
| SCHEMBL1782234 | 0.81 | HTRA1 (0.60) | HTRA1 | |
| SCHEMBL205497 | 0.81 | HTRA1 (0.60) | HTRA1 | |
| SCHEMBL4195796 | 0.81 | HTRA1 (0.60) | HTRA1 | |
| SCHEMBL13447272 | 0.81 | RIPK1 (0.44) | RIPK1CCKBRAGTR2HTRA1AKR1C3 | |
| SCHEMBL1243964 | 0.81 | HTRA1 (0.60) | HTRA1 | |
| SCHEMBL5201925 | 0.81 | HTRA1 (0.60) | HTRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050256166-A1 | Nitrogen-containing compounds | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-11-17 | — | — | US | disclosed |
| EP-1535906-A1 | NITROGEN-CONTAINING COMPOUNDS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-06-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256166-A1 | Nitrogen-containing compounds | DPP4, DPP3, DPP8 | RIPK1 2128/4885CCKBR 2585/4885AGTR2 627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.