SCHEMBL61861

SCHEMBL61861

O=C1CCN(C(=O)OCc2ccccc2)CC1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.66
MEN1 O00255 2/20 0.66
NPSR1 Q6W5P4 1/20 0.66
SMN1; SMN2 Q16637 3/20 0.64
NPC1 O15118 3/20 0.64
RAB9A P51151 3/20 0.64
CYP2C19 P33261 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.55
TMEM97 Q5BJF2 3/20 0.51
SIGMAR1 Q99720 3/20 0.51
GRIN2B Q13224 3/20 0.51
HTT P42858 1/20 0.51
GRM5 P41594 2/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C9 P11712 1/20 0.50
PKM P14618 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
POLB P06746 1/20 0.50
ALDH1A1 P00352 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL467515 0.94 MEN1 (0.59) KMT2AMEN1NPSR1SMN1; SMN2NPC1
SCHEMBL3614455 0.93 MEN1 (0.58) KMT2AMEN1NPSR1SMN1; SMN2NPC1
SCHEMBL3602428 0.91 MEN1 (0.62) KMT2AMEN1NPSR1SMN1; SMN2NPC1
SCHEMBL265902 0.91 MEN1 (0.58) KMT2AMEN1NPSR1SMN1; SMN2NPC1
Hydrochloric Acid SCHEMBL9207633 0.89 MEN1 (0.54) KMT2AMEN1NPSR1SMN1; SMN2NPC1
SCHEMBL4814264 0.88 MEN1 (0.76) KMT2AMEN1NPSR1SMN1; SMN2NPC1
SCHEMBL7393652 0.88 MEN1 (0.76) KMT2AMEN1NPSR1SMN1; SMN2NPC1
SCHEMBL3970912 0.88 MEN1 (0.76) KMT2AMEN1NPSR1SMN1; SMN2NPC1
SCHEMBL379160 0.88 MEN1 (0.76) KMT2AMEN1NPSR1SMN1; SMN2NPC1
SCHEMBL3612576 0.88 MEN1 (0.59) KMT2AMEN1NPSR1SMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2835 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1934561-B1 IMPROVED TIME/TEMPERATURE INDICATORS SUN CHEMICAL CORP (US) 2018-11-07 EP claimed
US-20080269050-A1 Time/Temperature Indicators SUN CHEMICAL CORPORATION (US) 2008-10-30 US claimed
EP-1934561-A1 IMPROVED TIME/TEMPERATURE INDICATORS Sun Chemical Corporation (US) 2008-06-25 EP claimed
WO-2007035365-A1 IMPROVED TIME/TEMPERATURE INDICATORS SUN CHEMICAL CORPORATION (US) 2007-03-29 WO claimed
WO-2006091465-A1 TIME/TEMPERATURE INDICATORS, THEIR PREPARATION AND USE SUN CHEMICAL CORPORATION (US) 2006-08-31 WO claimed
US-4477669-A Processes and intermediates useful in the preparation of flutroline PFIZER INC. (US) 1984-10-16 US claimed
EP-0082658-A2 Processes and intermediates useful in the preparation of flutroline PFIZER INC. (US) 1983-06-29 EP claimed
EP-4747253-A1 SPIROCYCLIC WRN HELICASE INHIBITORS Merck Sharp & Dohme LLC (US) 2026-05-27 EP disclosed
EP-4027995-B1 HPK1 ANTAGONISTS AND USES THEREOF NIMBUS SATURN INC (US) 2026-05-27 EP disclosed
WO-2026103730-A1 DIAZAHETEROCYCLIC DERIVATIVE OF PYRIDOARYL GROUP HAVING KAPPA RECEPTOR ANTAGONISTIC ACTIVITY AND COMPOSITION THEREOF, AND USE 江苏恩华药业股份有限公司 2026-05-21 WO disclosed
EP-4199925-B1 CYCLOPENTAPYRROLE OREXIN RECEPTOR AGONISTS MERCK SHARP & DOHME LLC (US) 2026-05-20 EP disclosed
CN-122070277-A Androgen receptor PROTAC 葛兰素史密斯克莱知识产权发展有限公司 2026-05-19 CN disclosed
CN-122070148-A Inhibitors of targeted fibroblast activation proteins 苏州博锐创合医药有限公司 2026-05-19 CN disclosed
EP-0082658-A2 Processes and intermediates useful in the preparation of flutroline PFIZER INC. (US) 1983-06-29 EP disclosed
US-4353901-A HYPERTENSION, CONGESTIVE HEART FAILURE, ARRHYTHMIAMIGRAINE, VASOSPASTIC DISORDERS, ASTHMA SYNTEX (U.S.A.) INC. (US) 1982-10-12 US disclosed
US-4353900-A HYPOTENSIVE, ANTIARRHYTHMIA, CARDIOTONIC, VASODILATORS SYNTEX (U.S.A.) INC. (US) 1982-10-12 US disclosed
EP-0061333-A1 9-(2-(3-Indolyl)ethyl)-1-oxa-4,9-diazaspiro(5.5)undecan-3-ones SYNTEX (U.S.A.) INC. (US) 1982-09-29 EP disclosed
US-4332804-A TREATMENT OF HYPERTENSION, CONGESTIVE HEART FAILURE, ARRHYTHMIA, MIGRAINE, VASOSPASTIC DISORDERS AND ASTHMA SYNTEX (U.S.A.) INC. (US) 1982-06-01 US disclosed
US-4255432-A ANTIHYPERTENSIVE AGENTS, ANTIHISTAMINES, BRONCHODILATOR AGENTS, ANTIVASOSPASTIC AGENTS SYNTEX (U.S.A.) INC. (US) 1981-03-10 US disclosed
US-4244961-A 1-Oxa-3,8-diazaspiro[4.5]decan-2-ones antihypertensive agents SYNTEX (U.S.A.) INC. (US) 1981-01-13 US disclosed