Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.69 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.64 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
| ▸ | CA5A | P35218 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4834727 | 0.84 | ACHE (0.72) | ACHESIGMAR1PKMKMT2A | |
| Hydrochloric Acid SCHEMBL6306233 | 0.83 | ACHE (0.70) | ACHESIGMAR1PKMKMT2A | |
| SCHEMBL1803484 | 0.80 | ACHE (0.69) | SPHK1HTR1AACHESIGMAR1DRD2 | |
| SCHEMBL20612472 | 0.80 | HRH3 (0.76) | HRH3SLC6A4SIGMAR1PKMKMT2A | |
| Hydrochloric Acid SCHEMBL11534786 | 0.79 | ACHE (0.67) | SPHK1ACHESIGMAR1SLC6A3KCNH2 | |
| Hydrochloric Acid SCHEMBL8788285 | 0.79 | ACHE (0.67) | SPHK1ACHESIGMAR1SLC6A3KCNH2 | |
| SCHEMBL2637536 | 0.79 | ACHE (0.64) | ACHESIGMAR1DRD4PKMKMT2A | |
| SCHEMBL4841995 | 0.79 | ACHE (0.64) | ACHESIGMAR1DRD4PKMKMT2A | |
| SCHEMBL4842070 | 0.79 | ACHE (0.64) | ACHESIGMAR1DRD4PKMKMT2A | |
| SCHEMBL8671948 | 0.78 | SLC6A4 (1.00) | HRH3SLC6A4SIGMAR1PKMSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534703-A2 | ANTAGONISTS OF MELANIN CONCENTRATING HORMONE RECEPTOR | ABBOTT LABORATORIES (US) | 2005-06-01 | — | — | EP | disclosed |
| WO-2003106452-A2 | ANTAGONISTS OF MELANIN CONCENTRATING HORMONE RECEPTOR | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2003-12-24 | — | — | WO | disclosed |