Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818072 | 0.76 | USP2 (0.48) | CYP2D6HDAC9ALDH1A1KMT2AMME | |
| SCHEMBL30492670 | 0.73 | BUB1 (0.40) | HTR2AALDH1A1KMT2A | |
| SCHEMBL7185718 | 0.73 | BUB1 (0.40) | HTR2AALDH1A1KMT2A | |
| SCHEMBL75787 | 0.73 | KDM1A (0.39) | HTR2AMAOAMAOBKDM1ADPP4 | |
| SCHEMBL20130556 | 0.73 | HTR2A (0.42) | HTR2AMAOAMAOBTAAR1CYP2D6 | |
| SCHEMBL21621578 | 0.71 | ADRA2A (0.39) | HTR2AMAOAMAOBTAAR1KDM1A | |
| SCHEMBL75539 | 0.70 | HTR2A (0.43) | HTR2AMAOAMAOBTAAR1HTR2C | |
| SCHEMBL18091534 | 0.70 | ESR2 (0.35) | KDM1ADPP4HDAC9MME | |
| Hydrochloric Acid SCHEMBL9515954 | 0.70 | ADRA2A (0.38) | HTR2AMAOAMAOBTAAR1HTR2C | |
| SCHEMBL24821401 | 0.67 | HDAC9 (0.35) | HTR2AHDAC9ALDH1A1KMT2AMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050256166-A1 | Nitrogen-containing compounds | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-11-17 | — | — | US | disclosed |
| EP-1535906-A1 | NITROGEN-CONTAINING COMPOUNDS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-06-01 | — | — | EP | disclosed |
| US-6166010-A | Azine derivatives | YASHIMA CHEMICAL INDUSTRY CO., LTD (JP) | 2000-12-26 | — | — | US | disclosed |
| EP-0635500-A1 | 5,6-Dihydro-(4H)1,3-oxazine and -thiazine derivatives as insecticides | YASHIMA CHEMICAL INDUSTRY CO., LTD. (JP) | 1995-01-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256166-A1 | Nitrogen-containing compounds | DPP4, DPP3, DPP8 | HTR2A 2421/4885MAOA 1806/4885MAOB 958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.