Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.57 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MC4R | P32245 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | MC3R | P41968 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27668658 | 0.86 | KDM4E (0.53) | KDM4ENAPRTHCAR2ADORA3TSHR | |
| SCHEMBL1911567 | 0.82 | KDM4E (0.57) | KDM4ENAPRTHCAR2ADORA3TSHR | |
| SCHEMBL5578127 | 0.81 | KDM4E (0.47) | KDM4ENAPRTHCAR2ADORA3TSHR | |
| SCHEMBL20705826 | 0.79 | KDM4E (0.53) | KDM4ENAPRTHCAR2ADORA3TSHR | |
| SCHEMBL11529414 | 0.78 | SMN1; SMN2 (0.48) | KDM4ENAPRTHCAR2ADORA3TSHR | |
| SCHEMBL11868873 | 0.78 | MAPT (0.47) | KDM4ENAPRTHCAR2ADORA3TSHR | |
| SCHEMBL8225877 | 0.76 | KDM4E (0.50) | KDM4ENAPRTHCAR2ADORA3TSHR | |
| Pyrazinoic Acid SCHEMBL8335237 | 0.76 | KDM4E (0.95) | KDM4ENAPRTHCAR2ADORA3TSHR | |
| Pyrazinoic Acid SCHEMBL8341710 | 0.76 | KDM4E (0.95) | KDM4ENAPRTHCAR2ADORA3TSHR | |
| SCHEMBL5160643 | 0.74 | GSK3B (0.59) | KDM4ENAPRTLMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1565460-A1 | METHOD FOR PREPARING OLTIPRAZ | CJ Corporation (KR) | 2005-08-24 | — | — | EP | claimed |
| WO-2004048369-A1 | METHOD FOR PREPARING OLTIPRAZ | CJ CORPORATION (KR) | 2004-06-10 | — | — | WO | claimed |
| WO-2023106973-A1 | NOVEL HEPATOPROTECTIVE AGENTS | ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "ВАЛЕНТА-ИНТЕЛЛЕКТ" | 2023-06-15 | — | — | WO | disclosed |
| EP-1565460-A1 | METHOD FOR PREPARING OLTIPRAZ | CJ Corporation (KR) | 2005-08-24 | — | — | EP | disclosed |
| EP-1565460-A1 | METHOD FOR PREPARING OLTIPRAZ | CJ Corporation (KR) | 2005-08-24 | — | — | EP | disclosed |
| WO-2004048369-A1 | METHOD FOR PREPARING OLTIPRAZ | CJ CORPORATION (KR) | 2004-06-10 | — | — | WO | disclosed |
| WO-2004048369-A1 | METHOD FOR PREPARING OLTIPRAZ | CJ CORPORATION (KR) | 2004-06-10 | — | — | WO | disclosed |