Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.70 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.70 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 6/20 | 0.60 |
| ▸ | RAB9A | P51151 | 6/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 4/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.60 |
| ▸ | RELA | Q04206 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6189280 | 0.84 | DYRK1A (0.68) | DYRK1ALRRK2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6186511 | 0.84 | DYRK1A (0.70) | DYRK1ANPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL6191383 | 0.84 | DYRK1A (0.76) | DYRK1ALRRK2ACP1 | |
| SCHEMBL3787846 | 0.84 | DYRK1A (0.76) | DYRK1APDPK1LRRK2NPC1RAB9A | |
| SCHEMBL6641942 | 0.82 | DYRK1A (0.74) | DYRK1APDPK1LRRK2NPC1RAB9A | |
| SCHEMBL15521825 | 0.82 | DYRK1A (1.00) | DYRK1APDPK1LRRK2NPC1RAB9A | |
| SCHEMBL13762152 | 0.82 | DYRK1A (0.64) | DYRK1APDPK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6191485 | 0.81 | NPC1 (0.72) | DYRK1ANPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL6193159 | 0.81 | DYRK1A (0.77) | DYRK1ANPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6190386 | 0.81 | ADORA1 (0.65) | DYRK1ANPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043319-B1 | NOVEL ALKYLAMINO DERIVATIVES | MITSUBISHI CHEM CORP (JP) | 2005-03-16 | — | — | EP | disclosed |
| EP-1043319-A1 | NOVEL ALKYLAMINO DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-10-11 | — | — | EP | disclosed |