Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.65 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 8/20 | 0.61 |
| ▸ | RAB9A | P51151 | 8/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.60 |
| ▸ | RELA | Q04206 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | CASP3 | P42574 | 3/20 | 0.58 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.58 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.58 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11745024 | 0.85 | GAA (0.67) | ADORA1DYRK1ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9891526 | 0.84 | ADORA1 (0.69) | ADORA1DYRK1ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL32674581 | 0.82 | NPC1 (0.84) | ADORA1DYRK1ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27634788 | 0.82 | NPC1 (0.84) | ADORA1DYRK1ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29483685 | 0.81 | CSNK1D (0.64) | ADORA1DYRK1ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28521971 | 0.81 | CSNK1D (0.64) | ADORA1DYRK1ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6187983 | 0.81 | DYRK1A (0.70) | ADORA1DYRK1ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5211562 | 0.80 | ADORA1 (0.73) | ADORA1DYRK1ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1580942 | 0.80 | NPC1 (0.73) | ADORA1DYRK1ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6186511 | 0.80 | DYRK1A (0.70) | DYRK1ANPC1RAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043319-B1 | NOVEL ALKYLAMINO DERIVATIVES | MITSUBISHI CHEM CORP (JP) | 2005-03-16 | — | — | EP | disclosed |
| EP-1043319-A1 | NOVEL ALKYLAMINO DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-10-11 | — | — | EP | disclosed |