Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 3/20 | 0.56 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM6B | O15054 | 1/20 | 0.37 |
| ▸ | KDM5C | P41229 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4811364 | 0.95 | ECE1 (0.60) | ECE1FAAHCNR1CNR2PRMT1 | |
| SCHEMBL9717431 | 0.85 | ECE1 (0.65) | ECE1FAAHCNR1CNR2PRMT1 | |
| SCHEMBL8531287 | 0.82 | ECE1 (0.62) | ECE1FAAHCNR1CNR2ITGB3 | |
| SCHEMBL13465545 | 0.82 | EPHX2 (0.49) | FAAHCNR1CNR2PRMT1TSHR | |
| SCHEMBL19607968 | 0.81 | ATM (0.53) | ECE1PRMT1TSHRKDM4ELMNA | |
| SCHEMBL6188305 | 0.81 | ECE1 (0.56) | ECE1FAAHCNR1CNR2PRMT1 | |
| SCHEMBL9717391 | 0.80 | ECE1 (0.60) | ECE1FAAHCNR1CNR2PRMT1 | |
| SCHEMBL9717382 | 0.80 | ECE1 (0.60) | ECE1FAAHCNR1CNR2PRMT1 | |
| SCHEMBL9717468 | 0.79 | ECE1 (0.81) | ECE1FAAHCNR1CNR2PRMT1 | |
| SCHEMBL17951118 | 0.79 | ADRA1A (0.57) | ECE1FAAHCNR1CNR2PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521742-A1 | DIPHENYLAZETIDINONE DERIVATIVES FOR TREATING DISORDERS OF THE LIPID METABOLISM | AstraZeneca AB (SE) | 2005-04-13 | — | — | EP | disclosed |
| WO-2004005247-A1 | DIPHENYLAZETIDINONE DERIVATIVES FOR TREATING DISORDERS OF THE LIPID METABOLISM | ASTRAZENECA AB (SE) | 2004-01-15 | — | — | WO | disclosed |