Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11229697 | 0.83 | GAA (0.33) | MEN1KMT2A | |
| SCHEMBL11309108 | 0.79 | SLC15A1 (0.41) | — | |
| SCHEMBL9400688 | 0.79 | ATM (0.39) | — | |
| SCHEMBL15080636 | 0.76 | — | — | |
| SCHEMBL12801402 | 0.75 | — | — | |
| SCHEMBL7204043 | 0.74 | — | — | |
| SCHEMBL1593747 | 0.71 | MEN1 (0.38) | TP53MEN1KMT2A | |
| SCHEMBL11304900 | 0.71 | SLC7A5 (0.50) | — | |
| SCHEMBL6517566 | 0.69 | — | — | |
| SCHEMBL346338 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532128-A1 | INHIBITORS OF HCV NS5B POLYMERASE | Pharmacia & Upjohn Company LLC (US) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002977-A1 | INHIBITORS OF HCV NS5B POLYMERASE | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-01-08 | — | — | WO | disclosed |