Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 11/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5950578 | 0.85 | MAPT (0.48) | ALDH1A1NPC1GAARAB9AL3MBTL1 | |
| SCHEMBL6224994 | 0.84 | TSHR (0.46) | ALDH1A1NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL5950126 | 0.83 | MAPT (0.43) | ALDH1A1NPC1GAARAB9AL3MBTL1 | |
| SCHEMBL5950379 | 0.83 | MAPT (0.50) | ALDH1A1NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL4024368 | 0.83 | HPGD (0.45) | ALDH1A1NPC1GAARAB9AL3MBTL1 | |
| SCHEMBL6258779 | 0.82 | CSF1R (0.34) | ALDH1A1MAPK1PDK2FLT3AR | |
| SCHEMBL5950007 | 0.81 | HPGD (0.42) | ALDH1A1NPC1RAB9AHPGDKMT2A | |
| SCHEMBL5468822 | 0.78 | MAPT (0.47) | ALDH1A1NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL27974522 | 0.78 | HPGD (0.55) | ALDH1A1NPC1GAARAB9AL3MBTL1 | |
| SCHEMBL5950251 | 0.77 | SMN1; SMN2 (0.49) | ALDH1A1NPC1RAB9AHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2005538152-A | — | — | 2005-12-15 | — | — | JP | claimed |
| EP-1537075-A2 | DIARYLUREA DERIVATIVES AND THEIR USE AS CHLORIDE CHANNEL BLOCKERS | NEUROSEARCH A/S (DK) | 2005-06-08 | — | — | EP | claimed |
| WO-2004022529-A2 | DIARYLUREA DERIVATIVES AND THEIR USE AS CHLORIDE CHANNEL BLOCKERS | NEUROSEARCH A/S (DK) | 2004-03-18 | — | — | WO | claimed |