Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 3/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 5/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 3/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.33 |
| ▸ | FYN | P06241 | 2/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | PAK4 | O96013 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27721400 | 0.84 | NPC1 (0.41) | CYP1A2CDK2CDK1ALDH1A1CCNE2 | |
| SCHEMBL6184029 | 0.84 | HIF1A (0.40) | — | |
| SCHEMBL6188567 | 0.82 | ALDH1A1 (0.44) | MAPK1FLT3PDK2ALDH1A1AR | |
| SCHEMBL6231660 | 0.81 | ALDH1A1 (0.41) | CYP1A2CDK2CDK1ALDH1A1CCNE2 | |
| SCHEMBL27449399 | 0.81 | KIF11 (0.46) | CYP1A2TOP2ANTRK1ALDH1A1 | |
| SCHEMBL6782273 | 0.80 | CYP1A2 (0.41) | CHEK2CYP1A2ALDH1A1 | |
| SCHEMBL17826231 | 0.78 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL23752073 | 0.78 | KCNMA1 (0.50) | CSF1RFYNABL1NTRK1LCK | |
| SCHEMBL1577476 | 0.76 | PARP1 (0.40) | CHEK2CDK2PDK2ARCCNE2 | |
| SCHEMBL3376022 | 0.76 | CHEK2 (0.43) | CHEK2CDK2CHEK1CDC7PLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1526851-A2 | COMPOUNDS USEFUL FOR THE TREATMENT OF DISEASES RESPONSIVE TO ANTIANGIOGENETIC THERAPY | NEUROSEARCH A/S (DK) | 2005-05-04 | — | — | EP | disclosed |
| WO-2004012733-A2 | COMPOUNDS USEFUL FOR THE TREATMENT OF DISEASES RESPONSIVE TO ANTIANGIOGENETIC THERAPY | NEUROSEARCH A/S (DK) | 2004-02-12 | — | — | WO | disclosed |