Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 19/20 | 0.66 |
| ▸ | OPRM1 | P35372 | 16/20 | 0.66 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5216223 | 0.87 | OPRD1 (0.68) | OPRD1OPRM1OPRK1KCNH2ABCB11 | |
| SCHEMBL5212203 | 0.87 | OPRD1 (0.68) | OPRD1OPRM1OPRK1KCNH2ABCB11 | |
| SCHEMBL5213514 | 0.85 | OPRD1 (0.66) | OPRD1OPRM1OPRK1KCNH2ABCB11 | |
| SCHEMBL5212759 | 0.85 | OPRD1 (0.66) | OPRD1OPRM1OPRK1KCNH2ABCB11 | |
| SCHEMBL5215388 | 0.85 | OPRD1 (0.71) | OPRD1OPRM1OPRK1KCNH2ABCB11 | |
| SCHEMBL5217382 | 0.85 | OPRD1 (0.77) | OPRD1OPRM1OPRK1KCNH2ABCB11 | |
| SCHEMBL5215976 | 0.84 | OPRD1 (0.72) | OPRD1OPRM1OPRK1KCNH2ABCB11 | |
| SCHEMBL5214067 | 0.83 | OPRD1 (0.68) | OPRD1OPRM1OPRK1KCNH2ABCB11 | |
| SCHEMBL14541243 | 0.83 | OPRD1 (0.64) | OPRD1OPRM1OPRK1KCNH2ABCB11 | |
| SCHEMBL5215538 | 0.83 | OPRD1 (0.64) | OPRD1OPRM1OPRK1KCNH2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567496-A1 | PHENYL-PIPERIDIN-4-YLIDENE-METHYL-BENZAMIDE DERIVATIVES FOR THE TREATMENT OF PAIN OR GASTROINTESTINAL DISORDERS | AstraZeneca AB (SE) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004041784-A1 | PHENYL-PIPERIDIN-4-YLIDENE-METHYL-BENZAMIDE DERIVATIVES FOR THE TREATMENT OF PAIN OR GASTROINTESTINAL DISORDERS | ASTRAZENECA AB (SE) | 2004-05-21 | — | — | WO | disclosed |