Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 12/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3535869 | 0.87 | PTGER4 (0.42) | PTGER4ALDH1A1HPGDPTGS2KDM4E | |
| SCHEMBL3534146 | 0.81 | PTGER4 (0.59) | PTGER4ALDH1A1HPGDKDM4EPOLB | |
| SCHEMBL3536680 | 0.79 | PTGER4 (0.61) | PTGER4ALDH1A1HPGDKDM4EPOLB | |
| SCHEMBL4119396 | 0.74 | PTGER4 (0.54) | PTGER4ALDH1A1HPGD | |
| SCHEMBL14072914 | 0.70 | APEX1 (0.49) | PTGER4ALDH1A1HPGDKDM4EPOLB | |
| SCHEMBL14620144 | 0.68 | APEX1 (0.53) | PTGER4ALDH1A1HPGDKDM4EPOLB | |
| SCHEMBL26186129 | 0.67 | CHRNB2 (0.56) | ALDH1A1PTGS2 | |
| SCHEMBL3536407 | 0.66 | PTGER4 (0.69) | PTGER4POLB | |
| SCHEMBL1756460 | 0.66 | PTGER4 (1.00) | PTGER4 | |
| SCHEMBL2981247 | 0.65 | CHRNB2 (0.60) | ALDH1A1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603893-A1 | EP4 RECEPTOR ANTAGONISTS | Pharmagene Laboratories Ltd (GB) | 2005-12-14 | — | — | EP | disclosed |
| WO-2004067524-A1 | EP4 RECEPTOR ANTAGONISTS | PHARMAGENE LABORATORIES LIMITED (GB) | 2004-08-12 | — | — | WO | disclosed |