Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 9/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 9/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.50 |
| ▸ | BPTF | Q12830 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 6/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 6/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6188672 | 0.80 | CHRNB2 (0.51) | CHRNB2CHRNA4CHRNA7BPTFCHRNB4 | |
| SCHEMBL1527035 | 0.79 | CHRNB2 (0.50) | CHRNB2CHRNA4CHRNA7BPTFCHRNB4 | |
| SCHEMBL1527033 | 0.79 | CHRNB2 (0.50) | CHRNB2CHRNA4CHRNA7BPTFCHRNB4 | |
| SCHEMBL6187336 | 0.78 | CHRNB2 (0.69) | CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3 | |
| SCHEMBL6350419 | 0.75 | CHRNB2 (0.66) | CHRNB2CHRNA4 | |
| SCHEMBL650890 | 0.71 | CHRNB2 (0.70) | CHRNB2CHRNA4CHRNA7BPTFCHRNB4 | |
| SCHEMBL650891 | 0.71 | CHRNB2 (0.70) | CHRNB2CHRNA4CHRNA7BPTFCHRNB4 | |
| SCHEMBL650815 | 0.71 | CHRNB2 (0.60) | CHRNB2CHRNA4CHRNA7BPTFCHRNB4 | |
| SCHEMBL6191046 | 0.71 | CHRNB2 (0.60) | CHRNB2CHRNA4CHRNA7BPTFCHRNB4 | |
| SCHEMBL6190806 | 0.71 | CHRNB2 (0.60) | CHRNB2CHRNA4CHRNA7BPTFCHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1274710-B1 | NOVEL HETEROARYL-DIAZABICYCLOALKANES | NEUROSEARCH AS (DK) | 2005-02-23 | — | — | EP | claimed |
| EP-1554274-A1 | 1-ACYL-PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | GLAXO GROUP LIMITED (GB) | 2005-07-20 | — | — | EP | disclosed |
| WO-2004037818-A1 | 1-ACYL-PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | GLAXO GROUP LIMITED (GB) | 2004-05-06 | — | — | WO | disclosed |