Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6421143 | 0.87 | TDP1 (0.46) | POLBTDP1MEN1KMT2ANPC1 | |
| SCHEMBL6176786 | 0.85 | POLB (0.51) | POLBMEN1KMT2ANPC1KDM4E | |
| SCHEMBL6414031 | 0.84 | POLB (0.44) | POLBMEN1KMT2ANPC1KDM4E | |
| SCHEMBL6414971 | 0.84 | POLB (0.50) | POLBMEN1KMT2ANPC1KDM4E | |
| SCHEMBL6419494 | 0.84 | POLB (0.50) | POLBMEN1KMT2ANPC1KDM4E | |
| SCHEMBL6190892 | 0.84 | HSD17B10 (0.53) | POLBMEN1KMT2AMAPT | |
| SCHEMBL6414717 | 0.84 | POLB (0.45) | POLBMEN1KMT2ANPC1KDM4E | |
| SCHEMBL6414969 | 0.83 | POLB (0.49) | POLBMEN1KMT2ANPC1KDM4E | |
| SCHEMBL5657975 | 0.82 | MAPT (0.59) | MEN1KMT2ANPC1KDM4EMAPT | |
| SCHEMBL14457597 | 0.81 | DRD2 (0.52) | POLBTDP1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1530564-A2 | COMPOUNDS DERIVED FROM ARYL CARBAMATES, PREPARATION THEREOF AND USES OF SAME | Cerep (FR) | 2005-05-18 | — | — | EP | claimed |
| WO-2004018436-A2 | COMPOUNDS DERIVED FROM ARYL CARBAMATES, PREPARATION THEREOF AND USES OF SAME | CEREP (FR) | 2004-03-04 | — | — | WO | claimed |
| EP-1530564-A2 | COMPOUNDS DERIVED FROM ARYL CARBAMATES, PREPARATION THEREOF AND USES OF SAME | Cerep (FR) | 2005-05-18 | — | — | EP | disclosed |
| WO-2004018436-A2 | COMPOUNDS DERIVED FROM ARYL CARBAMATES, PREPARATION THEREOF AND USES OF SAME | CEREP (FR) | 2004-03-04 | — | — | WO | disclosed |