SCHEMBL6192086

SCHEMBL6192086

CCCCc1ccccc1C(=O)NC

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PLK1 P53350 3/20 0.51
HTT P42858 2/20 0.50
TSHR P16473 2/20 0.50
GAA P10253 2/20 0.49
ALDH1A1 P00352 2/20 0.44
HPGD P15428 3/20 0.44
ADRB2 P07550 1/20 0.44
KDR P35968 1/20 0.44
NAAA Q02083 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
SLC16A3 O15427 1/20 0.43
L3MBTL1 Q9Y468 3/20 0.42
LMNA P02545 2/20 0.42
KDM4E B2RXH2 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
LIPG Q9Y5X9 1/20 0.42
TDP1 Q9NUW8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27354499 0.98 PLK1 (0.50) PLK1HTTTSHRGAAALDH1A1
SCHEMBL15923268 0.95 HTT (0.49) PLK1HTTTSHRGAAALDH1A1
SCHEMBL11039198 0.93 LIPG (0.51) PLK1HTTTSHRGAAALDH1A1
SCHEMBL13705878 0.89 GAA (0.52) PLK1HTTTSHRGAAALDH1A1
SCHEMBL11148178 0.86 HTT (0.50) HTTTSHRGAAALDH1A1HPGD
SCHEMBL4054015 0.86 HTT (0.50) HTTTSHRALDH1A1HPGDADRB2
SCHEMBL5954191 0.83 GAA (0.57) PLK1HTTTSHRGAAALDH1A1
Hydrochloric Acid SCHEMBL9298722 0.83 KDR (0.48) PLK1HTTTSHRALDH1A1HPGD
SCHEMBL21590248 0.83 TSHR (0.49) PLK1HTTTSHRGAAALDH1A1
SCHEMBL21192538 0.82 GAA (0.56) PLK1HTTGAAALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239934-A1 FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE TOSOH CORPORATION (JP) 2024-07-18 US disclosed
US-20240239934-A1 FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE TOSOH CORPORATION (JP) 2024-07-18 US disclosed
CN-103214329-B Preparation method of N-methylformamide catalyzed by metallic copper salt UNIV ZHEJIANG 2014-12-10 CN disclosed
CN-103214329-A Preparation method of N-methylformamide catalyzed by metallic copper salt UNIV ZHEJIANG 2013-07-24 CN disclosed
EP-1521746-A1 QUINAZOLINONE MODULATORS OF NUCLEAR RECEPTORS X-Ceptor Therapeutics, Inc. (US) 2005-04-13 EP disclosed
WO-2003076418-A1 QUINAZOLINONE MODULATORS OF NUCLEAR RECEPTORS X-CEPTOR THERAPEUTICS, INC. (US) 2003-09-18 WO disclosed
CN-1119861-A 1-phenyl-imidazol-2-one biphenylmethyl compounds for treatment of circulatory disorders SEARLE & CO (US) 1996-04-03 CN disclosed
CN-1094723-A Carboxamide derivative ZENECA LTD (GB) 1994-11-09 CN disclosed
EP-0555331-A1 N-SUBSTITUTED IMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS. SEARLE & CO (US) 1993-08-18 EP disclosed