Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | IKBKB | O14920 | 2/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6195929 | 0.87 | ADORA3 (0.35) | CDK4MAPK14MAPK9MAPK10CHRNA7 | |
| SCHEMBL6569263 | 0.68 | CDK4 (0.39) | CDK4MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL1034820 | 0.67 | CDK4 (0.57) | CDK4MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL6191903 | 0.67 | CSNK1D (0.47) | CDK4MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL6194667 | 0.63 | CSNK1D (0.45) | CDK4MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL21621306 | 0.63 | CDK4 (0.63) | CDK4MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL5452916 | 0.63 | CSNK1D (0.51) | CDK4MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL6196226 | 0.62 | CSNK1D (0.46) | CDK4MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL5726060 | 0.62 | CSNK1D (0.51) | CDK4MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL5890649 | 0.62 | CSNK1D (0.51) | CDK4MAPK13MAPK12MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1385847-B1 | PYRAZOLO[1,5-A]PYRIDINE DERIVATIVES | SMITHKLINE BEECHAM CORP (US) | 2005-06-01 | — | — | EP | claimed |