Sugi Predict

Sugi Predict / Compounds / Benzamide

Benzamide

Benzamide

SCHEMBL6192590

COc1ccc(-c2ccccc2OCc2cc(S(=O)(=O)O)oc2C)cc1.NC(=O)c1ccccc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ PTGER4 P35408 16/20 0.54
▸ PARP1 P09874 1/20 0.43
▸ AKR1C1 Q04828 1/20 0.43
▸ LMNA P02545 1/20 0.42
▸ MAPK1 P28482 1/20 0.42
▸ HTT P42858 1/20 0.42
▸ TDP1 Q9NUW8 1/20 0.42
▸ L3MBTL1 Q9Y468 1/20 0.42
▸ SYK P43405 1/20 0.41
▸ AURKB Q96GD4 1/20 0.41
▸ INCENP Q9NQS7 1/20 0.41
▸ PTGER1 P34995 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzamide SCHEMBL3533359 0.90 PTGER4 (0.57) PTGER4
Benzamide SCHEMBL3540624 0.85 PTGER4 (0.58) PTGER4
SCHEMBL6192592 0.84 PTGER4 (0.62) PTGER4
Benzamide SCHEMBL6192907 0.82 PTGER4 (0.53) PTGER4
SCHEMBL3536141 0.78 PTGER4 (0.64) PTGER4
SCHEMBL6192373 0.76 PTGER4 (0.51) PTGER4PARP1AKR1C1LMNAMAPK1
SCHEMBL3537522 0.76 PTGER4 (0.65) PTGER4
SCHEMBL6192187 0.75 PTGER4 (0.59) PTGER4LMNASYKAURKBINCENP
SCHEMBL3533356 0.72 PTGER4 (0.69) PTGER4
SCHEMBL3537906 0.70 PTGER4 (1.00) PTGER4TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1603893-A1 EP4 RECEPTOR ANTAGONISTS Pharmagene Laboratories Ltd (GB) 2005-12-14 — — EP disclosed
WO-2004067524-A1 EP4 RECEPTOR ANTAGONISTS PHARMAGENE LABORATORIES LIMITED (GB) 2004-08-12 — — WO disclosed