SCHEMBL6192592

SCHEMBL6192592

COc1ccc(-c2ccccc2OCc2cc(S(=O)(=O)NC(=O)c3ccccc3)oc2C)cc1

nearest known ligand 0.62

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 20/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3533356 0.90 PTGER4 (0.69) PTGER4
SCHEMBL3540622 0.85 PTGER4 (0.68) PTGER4
Benzamide SCHEMBL6192590 0.84 PTGER4 (0.54) PTGER4
SCHEMBL6192904 0.82 PTGER4 (0.62) PTGER4
SCHEMBL4690885 0.79 PTGER4 (0.62) PTGER4
SCHEMBL4687516 0.76 PTGER4 (0.59) PTGER4
SCHEMBL3532321 0.76 PTGER4 (1.00) PTGER4
SCHEMBL6192187 0.75 PTGER4 (0.59) PTGER4
SCHEMBL6192373 0.74 PTGER4 (0.51) PTGER4
SCHEMBL4691018 0.74 PTGER4 (0.61) PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1603893-A1 EP4 RECEPTOR ANTAGONISTS Pharmagene Laboratories Ltd (GB) 2005-12-14 EP disclosed
WO-2004067524-A1 EP4 RECEPTOR ANTAGONISTS PHARMAGENE LABORATORIES LIMITED (GB) 2004-08-12 WO disclosed