Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 8/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 8/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.39 |
| ▸ | CDK2AP1 | O14519 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6193108 | 0.95 | BCL9 (0.43) | BCL9CTNNB1MKNK1MKNK2CHEK1 | |
| SCHEMBL6193112 | 0.95 | BCL9 (0.43) | BCL9CTNNB1MKNK1MKNK2CHEK1 | |
| SCHEMBL4028234 | 0.88 | BCL9 (0.52) | BCL9CTNNB1 | |
| SCHEMBL4027810 | 0.88 | BCL9 (0.52) | BCL9CTNNB1 | |
| SCHEMBL5362032 | 0.88 | BCL9 (0.52) | BCL9CTNNB1 | |
| SCHEMBL4028110 | 0.82 | CYP11B2 (0.51) | MKNK1MKNK2ABL1CYP19A1CYP11B1 | |
| Cadaverine Tartrate SCHEMBL4027502 | 0.81 | BCL9 (0.49) | BCL9CTNNB1 | |
| SCHEMBL5505486 | 0.77 | BCL9 (0.54) | BCL9CTNNB1 | |
| SCHEMBL5348343 | 0.77 | PPARA (0.48) | BCL9CTNNB1 | |
| SCHEMBL5361918 | 0.77 | PPARA (0.48) | BCL9CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567493-A1 | PHENYL SUBSTITUTED PIPERIDINE COMPOUNDS FOR USE AS PPAR ACTIVATORS | Pfizer Products Inc. (US) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004048334-A1 | PHENYL SUBSTITUTED PIPERIDINE COMPOUNDS FOR USE AS PPAR ACTIVATORS | PFIZER PRODUCTS INC. (US) | 2004-06-10 | — | — | WO | disclosed |