SCHEMBL619429

SCHEMBL619429

COOc1c(O)cc(C(=O)O)c(OC)c1OOC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TPMT P51580 5/20 0.47
HSD17B10 Q99714 2/20 0.47
TDP1 Q9NUW8 2/20 0.43
MAPT P10636 1/20 0.43
ALDH1A1 P00352 2/20 0.40
KDM4E B2RXH2 2/20 0.40
HPGD P15428 1/20 0.40
PKM P14618 2/20 0.38
LCK P06239 1/20 0.38
FYN P06241 1/20 0.38
PTGS2 P35354 1/20 0.38
GAA P10253 1/20 0.37
ALOX15 P16050 1/20 0.37
GPR35 Q9HC97 1/20 0.37
HTT P42858 1/20 0.37
APP P05067 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA3 P07451 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10920985 0.92 KDM4E (0.45) TPMTHSD17B10TDP1MAPTALDH1A1
SCHEMBL10623344 0.84 CA12 (0.44) TPMTHSD17B10TDP1MAPTALDH1A1
SCHEMBL419090 0.77 TDP1 (0.50) TPMTHSD17B10TDP1MAPTALDH1A1
SCHEMBL31058988 0.77 TDP1 (0.61) TPMTHSD17B10TDP1MAPTALDH1A1
SCHEMBL670626 0.76 TPMT (0.49) TPMTHSD17B10TDP1MAPTKDM4E
SCHEMBL25378470 0.74 TPMT (0.47) TPMTHSD17B10TDP1MAPTKDM4E
SCHEMBL13064871 0.74 KDM4E (0.49) TPMTHSD17B10TDP1MAPTALDH1A1
SCHEMBL10355393 0.74 HSD17B10 (0.71) TPMTHSD17B10TDP1MAPTALDH1A1
SCHEMBL18677528 0.73 TDP1 (0.55) TPMTHSD17B10TDP1MAPTALDH1A1
SCHEMBL13064873 0.73 TPMT (0.46) TPMTHSD17B10TDP1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4756950-A Support, heat meltable ink layer comprising dye, saturated polyester MITSUBISHI PAPER MILLS, LTD. (JP) 1988-07-12 US claimed
US-20120252666-A1 THERMALLY SENSITIVE RECORDING MATERIAL MONDI UNCOATED FINE & KRAFT PAPER GMBH (AT) 2012-10-04 US disclosed
EP-2504175-A1 THERMALLY SENSITIVE RECORDING MATERIAL Mondi Uncoated Fine & Kraft Paper GmbH (AT) 2012-10-03 EP disclosed
US-20120038701-A1 METHOD FOR THE COLOUR-IMPARTING INSCRIBING OF SURFACES MONDI UNCOATED FINE & KRAFT PAPER GMBH (AT) 2012-02-16 US disclosed
WO-2011063919-A1 THERMALLY SENSITIVE RECORDING MATERIAL MONDI UNCOATED FINE & KRAFT PAPER GMBH (AT) 2011-06-03 WO disclosed
EP-2325018-A1 Thermally sensitive recording material Mondi Uncoated Fine & Kraft Paper GmbH (AT) 2011-05-25 EP disclosed
EP-2264110-A1 Reactive ink for chromophoric illustration of surfaces Mondi Uncoated Fine & Kraft Paper GmbH (AT) 2010-12-22 EP disclosed
WO-2010072388-A2 METHOD FOR THE COLOUR-IMPARTING INSCRIBING OF SURFACES MONDI UNCOATED FINE & KRAFT PAPER GMBH (AT) 2010-07-01 WO disclosed
EP-2199094-A1 Method for chromophoric illustration of surfaces Mondi Uncoated Fine & Kraft Paper GmbH (AT) 2010-06-23 EP disclosed
US-4756950-A Support, heat meltable ink layer comprising dye, saturated polyester MITSUBISHI PAPER MILLS, LTD. (JP) 1988-07-12 US disclosed