SCHEMBL10920985

SCHEMBL10920985

COOc1c(O)cc(C(=O)O)c(OC)c1OOC.COOc1c(O)cc(C(=O)OC)c(OC)c1OOC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.45
ALDH1A1 P00352 2/20 0.45
HPGD P15428 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
POLB P06746 4/20 0.43
MAPT P10636 2/20 0.43
NPC1 O15118 1/20 0.43
ABL1 P00519 1/20 0.43
PKM P14618 1/20 0.43
RECQL P46063 1/20 0.43
BLM P54132 1/20 0.43
BCL2L1 Q07817 1/20 0.43
MCL1 Q07820 1/20 0.43
RIN1 Q13671 1/20 0.43
SAE1 Q9UBE0 1/20 0.43
UBA2 Q9UBT2 1/20 0.43
TPMT P51580 4/20 0.41
HSD17B10 Q99714 2/20 0.41
CA12 O43570 3/20 0.40
CA1 P00915 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10623344 0.94 CA12 (0.44) KDM4EALDH1A1HPGDNPSR1POLB
SCHEMBL619429 0.92 TPMT (0.47) KDM4EALDH1A1HPGDMAPTPKM
SCHEMBL30912978 0.74 CA12 (0.57) KDM4EALDH1A1HPGDPOLBMAPT
SCHEMBL30810271 0.73 KDM4E (0.53) KDM4EALDH1A1HPGDNPSR1POLB
SCHEMBL6852883 0.72 MAPT (0.52) KDM4EALDH1A1HPGDNPSR1POLB
SCHEMBL669967 0.71 CA12 (0.46) KDM4EALDH1A1HPGDNPSR1POLB
SCHEMBL31058988 0.71 TDP1 (0.61) KDM4EALDH1A1HPGDMAPTNPC1
SCHEMBL419090 0.71 TDP1 (0.50) KDM4EALDH1A1HPGDMAPTPKM
SCHEMBL11046315 0.71 MAPT (0.50) KDM4EALDH1A1HPGDNPSR1POLB
SCHEMBL14870982 0.69 CA12 (0.52) KDM4EALDH1A1HPGDPOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-61242892-A None JP disclosed
JP-S61242892-A GRADATABLE THERMAL TRANSFER RECORDING SHEET MITSUBISHI PAPER MILLS LTD 1986-10-29 JP disclosed