Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6196012 | 0.88 | MAPK1 (0.41) | MAPK1RXFP1EGLN1TP53LIPG | |
| SCHEMBL6199108 | 0.85 | KMT2A (0.47) | EGLN1LMNATHRBNR3C1 | |
| SCHEMBL6195907 | 0.82 | MAPK1 (0.44) | MAPK1EGLN1LMNATHRBNR3C1 | |
| SCHEMBL6198591 | 0.81 | EGLN1 (0.49) | EGLN1CNR2LMNANR3C1CYP1A2 | |
| SCHEMBL6195978 | 0.79 | KMT2A (0.47) | EGLN1LMNANR3C1 | |
| SCHEMBL6222048 | 0.79 | EGLN1 (0.38) | MAPK1RXFP1EGLN1TP53LIPG | |
| SCHEMBL6202279 | 0.77 | MAPK1 (0.43) | MAPK1EGLN1LMNATHRBNR3C1 | |
| SCHEMBL6198524 | 0.77 | EGLN1 (0.51) | EGLN1CNR2LMNANR3C1CYP1A2 | |
| SCHEMBL6766761 | 0.76 | MAPK1 (0.45) | MAPK1RXFP1EGLN1TP53CNR2 | |
| SCHEMBL6198708 | 0.76 | EGLN1 (0.44) | EGLN1LMNANR3C1PTGER4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | claimed |