Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | POLA1 | P09884 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6195907 | 0.93 | MAPK1 (0.44) | MAPK1EGLN1LMNANR3C1SMN1; SMN2 | |
| SCHEMBL6198735 | 0.92 | MAPK1 (0.43) | MAPK1EGLN1LMNANR3C1SMN1; SMN2 | |
| SCHEMBL6195899 | 0.88 | MAPK1 (0.43) | MAPK1EGLN1LMNANR3C1SMN1; SMN2 | |
| SCHEMBL6195978 | 0.88 | KMT2A (0.47) | EGLN1LMNANR3C1SMN1; SMN2MAPT | |
| SCHEMBL6199268 | 0.87 | MAPK1 (0.44) | MAPK1EGLN1LMNANR3C1SMN1; SMN2 | |
| SCHEMBL6199108 | 0.87 | KMT2A (0.47) | EGLN1LMNANR3C1SMN1; SMN2THRB | |
| SCHEMBL6198708 | 0.85 | EGLN1 (0.44) | EGLN1LMNANR3C1SMN1; SMN2MAPT | |
| SCHEMBL8122619 | 0.84 | NR3C1 (0.43) | EGLN1LMNANR3C1SMN1; SMN2THRB | |
| SCHEMBL6197307 | 0.81 | EGLN1 (0.44) | EGLN1LMNANR3C1SMN1; SMN2MAPT | |
| SCHEMBL6199670 | 0.81 | EGLN1 (0.41) | MAPK1EGLN1LMNANR3C1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | claimed |