Methane

Methane

SCHEMBL6196689

C.O=CCCOS(=O)(=O)O

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.33
CA9 Q16790 1/20 0.33
FNTA P49354 1/20 0.32
FNTB P49356 1/20 0.32
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7036524 0.97
SCHEMBL8522575 0.81 FNTA (0.41) CA2CA9FNTAFNTBHIF1A
SCHEMBL6704245 0.79 FNTA (0.43) CA2CA9FNTAFNTBHIF1A
SCHEMBL3263854 0.79 FNTA (0.43) CA2CA9FNTAFNTBHIF1A
SCHEMBL17469879 0.79 CA2 (0.36) CA2CA9FNTAFNTB
Ammonia Solution, Strong SCHEMBL29176449 0.78 FNTA (0.42) CA2CA9FNTAFNTBHIF1A
SCHEMBL1258276 0.75
SCHEMBL6104909 0.75
SCHEMBL5969210 0.75
SCHEMBL562188 0.74 CA2 (0.44) CA2CA9FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1066304-B1 MACROLIDE LHRH ANTAGONISTS ABBOTT LAB (US) 2005-02-23 EP disclosed
EP-1066304-A1 MACROLIDE LHRH ANTAGONISTS ABBOTT LABORATORIES (US) 2001-01-10 EP disclosed
WO-1999050275-A2 MACROLIDE LHRH ANTAGONISTS ABBOTT LABORATORIES (US) 1999-10-07 WO disclosed
US-5955440-A 3'-N-DESMETHYL-3'-N-SUBSTITUTED-6-O-METHYL-11-DEOXY-11,12-CYCL IC CARBAMATE ERYTHROMYCIN A DERIVATIVES ABBOTT LABORATORIES (US) 1999-09-21 US disclosed