Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 5/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.59 |
| ▸ | DRD2 | P14416 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | HTR2A | P28223 | 1/20 | 0.59 |
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.59 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.59 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.50 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.50 |
| ▸ | IGF1R | P08069 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5527297 | 0.90 | UTS2R (0.54) | UTS2RADRA2ADRD2SLC6A2HTR2A | |
| SCHEMBL6198660 | 0.89 | CXCR3 (0.59) | UTS2RADRA2ADRD2SLC6A2HTR2A | |
| SCHEMBL6194469 | 0.88 | UTS2R (0.61) | UTS2RADRA2ADRD2SLC6A2HTR2A | |
| SCHEMBL4862060 | 0.86 | UTS2R (0.68) | UTS2RADRA2ADRD2SLC6A2HTR2A | |
| SCHEMBL5732907 | 0.86 | UTS2R (0.61) | UTS2RADRA2ADRD2SLC6A2HTR2A | |
| SCHEMBL6196245 | 0.86 | CXCR3 (0.55) | UTS2RADRA2ADRD2SLC6A2HTR2A | |
| Hydrochloric Acid SCHEMBL4851917 | 0.86 | UTS2R (0.67) | UTS2RADRA2ADRD2SLC6A2HTR2A | |
| SCHEMBL6195603 | 0.84 | UTS2R (0.66) | UTS2RADRA2ADRD2SLC6A2HTR2A | |
| SCHEMBL6199009 | 0.84 | UTS2R (0.65) | UTS2RADRA2ADRD2SLC6A2HTR2A | |
| SCHEMBL6197148 | 0.84 | UTS2R (0.65) | UTS2RADRA2ADRD2SLC6A2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499607-B1 | 4-(PIPERIDYL- AND PYRROLIDYL-ALKYL-UREIDO)-QUINOLINES AS UROTENSIN II RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2005-12-07 | — | — | EP | disclosed |