Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 9/20 | 0.59 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.59 |
| ▸ | PIK3CG | P48736 | 9/20 | 0.59 |
| ▸ | PIK3CB | P42338 | 8/20 | 0.59 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6197343 | 1.00 | PIK3CD (0.59) | PIK3CDPIK3CAPIK3CGPIK3CBAOC3 | |
| SCHEMBL4871157 | 0.90 | PIK3CA (0.57) | PIK3CDPIK3CAPIK3CGPIK3CBAOC3 | |
| SCHEMBL4871160 | 0.90 | PIK3CA (0.57) | PIK3CDPIK3CAPIK3CGPIK3CBAOC3 | |
| SCHEMBL4867086 | 0.86 | PIK3CD (0.57) | PIK3CDPIK3CAPIK3CGPIK3CBAOC3 | |
| SCHEMBL4867076 | 0.86 | PIK3CD (0.57) | PIK3CDPIK3CAPIK3CGPIK3CBAOC3 | |
| SCHEMBL6264646 | 0.83 | AOC3 (0.50) | PIK3CDPIK3CAPIK3CGPIK3CBAOC3 | |
| SCHEMBL6264653 | 0.83 | AOC3 (0.50) | PIK3CDPIK3CAPIK3CGPIK3CBAOC3 | |
| SCHEMBL4990287 | 0.78 | PIK3CD (0.60) | PIK3CDPIK3CAPIK3CGPIK3CBAOC3 | |
| SCHEMBL4990301 | 0.78 | PIK3CD (0.60) | PIK3CDPIK3CAPIK3CGPIK3CBAOC3 | |
| SCHEMBL4874768 | 0.75 | PIK3CD (0.65) | PIK3CDPIK3CAPIK3CGPIK3CBAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1587800-A1 | THIAZOLE DERIVATIVES AND THEIR USE AS VAP-1 INHIBITORS | Astellas Pharma Inc. (JP) | 2005-10-26 | — | — | EP | disclosed |
| WO-2004067521-A1 | THIAZOLE DERIVATIVES AND THEIR USE AS VAP-1 INHIBITORS | ASTELLAS PHARMA INC. (JP) | 2004-08-12 | — | — | WO | disclosed |