SCHEMBL6197489

SCHEMBL6197489

C=Cc1cc(OCC)cc(OCC)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.47
AHR P35869 1/20 0.47
NQO1 P15559 1/20 0.44
RELA Q04206 1/20 0.39
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CHRNB2 P17787 2/20 0.38
CHRNB4 P30926 2/20 0.38
CHRNA3 P32297 2/20 0.38
CHRNA7 P36544 2/20 0.38
CHRNA4 P43681 2/20 0.38
TSHR P16473 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ABL1 P00519 1/20 0.37
ABCB1 P08183 1/20 0.37
BCR P11274 1/20 0.37
TP53 P04637 1/20 0.36
CYP3A4 P08684 1/20 0.36
TUBB4A P04350 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16954499 0.92 ESR1 (0.59) ESR1AHRNQO1KDM4EALDH1A1
SCHEMBL27786572 0.92 ESR1 (0.59) ESR1AHRNQO1KDM4EALDH1A1
SCHEMBL16953268 0.89 AHR (0.49) ESR1AHRNQO1RELAKDM4E
SCHEMBL16951575 0.88 TDP1 (0.39) ESR1AHRNQO1RELAKDM4E
SCHEMBL16953947 0.86 FGFR1 (0.38) ESR1AHRNQO1RELAKDM4E
SCHEMBL16958269 0.86 ESR1 (0.38) ESR1AHRNQO1RELAKDM4E
SCHEMBL16957170 0.86 ESR1 (0.38) ESR1AHRNQO1RELAKDM4E
SCHEMBL5882501 0.86 KDM4E (0.45) ESR1AHRNQO1RELAKDM4E
SCHEMBL16955848 0.86 ESR1 (0.38) ESR1AHRNQO1RELAKDM4E
SCHEMBL16951241 0.86 MAPT (0.38) ESR1AHRNQO1RELAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104387524-B Film-forming resin containing sesquiterpene lactone and its negativity 248nm photoresists 昆山西迪光电材料有限公司 2017-06-16 CN claimed
CN-103387636-B Containing film-forming resin and the positivity 248nm photoresist material thereof of sesquiterpene KUNSHAN SD PHOTOELECTRIC MATERIAL CO., LTD. (CN) 2015-08-12 CN claimed
CN-104592436-A Sesquiterpene lactone-containing film-forming resin and positive 248 nm photoresist thereof KUNSHAN XIDI OPTOELECTRONIC MATERIAL CO LTD 2015-05-06 CN claimed
CN-104387524-A Sesquiterpene lactone-containing film-forming resin and negative 248nm photoresist thereof KUNSHAN XIDI OPTOELECTRONIC MATERIAL CO LTD 2015-03-04 CN claimed
CN-104387512-A Sesquiterpene-containing film forming resin and negative 248nm photoresist thereof KUNSHAN XIDI OPTOELECTRONIC MATERIAL CO LTD 2015-03-04 CN claimed
CN-103387636-A Sesquiterpene-containing film-forming resin and positive 248 nm photoresist thereof KUNSHAN SD PHOTOELECTRIC MATERIAL CO LTD 2013-11-13 CN claimed
CN-102050908-A Chemical amplitude-increasing type silicon-containing I-line ultraviolet negative photoresist and forming resin thereof KUNSHAN XIDI OPTOELECTRONIC MATERIAL CO LTD 2011-05-11 CN claimed
CN-101974121-A Chemical amplified high-resolution silicon-containing I-ray ultraviolet photoresist and forming resin thereof KUNSHAN XIDI ELECTRO OPTIC MATERIALS CO LTD 2011-02-16 CN claimed
CN-101463106-A Copolymer film forming resin containing benzoxazine structure and deep UV negativity chemical amplification type photo resist CHENGDU JINJIANG HI TECH MATER (CN) 2009-06-24 CN claimed
EP-1130017-B1 Azole derivatives and their use as superoxide radical inhibitors OTSUKA PHARMA CO LTD (JP) 2005-06-15 EP claimed
EP-3131638-A1 PROCESS FOR STYLING THE HAIR WITH A POLYVINYLPYRIDINE L'OREAL (FR) 2017-02-22 EP disclosed
CN-106456500-A Method of styling hair using polyvinylpyridine 莱雅公司 2017-02-22 CN disclosed
US-20170042785-A1 PROCESS FOR STYLING THE HAIR WITH A POLYVINYLPYRIDINE L'OREAL (FR) 2017-02-16 US disclosed
WO-2015158644-A1 PROCESS FOR STYLING THE HAIR WITH A POLYVINYLPYRIDINE L'OREAL (FR) 2015-10-22 WO disclosed
CN-103387636-B Containing film-forming resin and the positivity 248nm photoresist material thereof of sesquiterpene KUNSHAN SD PHOTOELECTRIC MATERIAL CO., LTD. (CN) 2015-08-12 CN disclosed
US-6080764-A PROTECTING VARIOUS TISSUE CELLS FROM DISTURBANCES ASSOCIATED WITH ISCHEMIA AND BLOOD REPERFUSION IN HEART, BRAIN, KIDNEY, LUNG AND DIGESTIVE TRACT BY INHIBITING SUPEROXIDE-RELEASE BY NEUTROPHILIC LEUKOCYTES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2000-06-27 US disclosed
EP-0934937-A1 Azole derivatives as superoxide radical inhibitor OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1999-08-11 EP disclosed
US-5677319-A THIAZOLE DERIVATIVE OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1997-10-14 US disclosed
US-5643932-A PREVENTS CELL DAMAGE AFTER ISCHEMIA AND RE-PERFUSION, SUBSTITUTED THIAZOLES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1997-07-01 US disclosed
EP-0513387-A1 ACTIVE OXYGEN INHIBITOR OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1992-11-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170042785-A1 PROCESS FOR STYLING THE HAIR WITH A POLYVINYLPYRIDINE PRKDC, POLR1C, PIK3C3 ESR1 4756/4885AHR 2477/4885NQO1 3946/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.