Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.50 |
| ▸ | ACACA | Q13085 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.41 |
| ▸ | CPT2 | P23786 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.39 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19678182 | 0.98 | ACACB (0.53) | ACACBACACAFFAR1FFAR4PTPN1 | |
| SCHEMBL6180003 | 0.91 | ACACB (0.59) | ACACBACACAFFAR1FFAR4PTPN1 | |
| SCHEMBL6695817 | 0.86 | GPR84 (0.54) | FFAR1FFAR4PTPN1TBXAS1CPT2 | |
| SCHEMBL6696708 | 0.86 | GPR84 (0.54) | FFAR1FFAR4PTPN1TBXAS1CPT2 | |
| SCHEMBL939882 | 0.85 | ACACB (0.72) | ACACBACACAFFAR1FFAR4TBXAS1 | |
| SCHEMBL5902926 | 0.85 | ACACB (0.40) | ACACBACACAFFAR1FFAR4PTPN1 | |
| SCHEMBL19678184 | 0.84 | ACACB (0.52) | ACACBACACAFFAR1FFAR4PTPN1 | |
| SCHEMBL5902654 | 0.84 | ACACB (0.42) | ACACBACACAFFAR1FFAR4PTPN1 | |
| SCHEMBL5902989 | 0.82 | ACACB (0.40) | ACACBACACAFFAR1FFAR4PTPN1 | |
| SCHEMBL5902913 | 0.81 | ACACB (0.42) | ACACBACACAFFAR1FFAR4PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1597223-A2 | HYDROXYL COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | Esperion Therapeutics Inc. (US) | 2005-11-23 | — | — | EP | disclosed |
| WO-2004067489-A2 | HYDROXYL COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. (US) | 2004-08-12 | — | — | WO | disclosed |