Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | KDM6A | O15550 | 1/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KDM5C | P41229 | 1/20 | 0.32 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6197640 | 0.86 | KDM4E (0.46) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL6196542 | 0.85 | KMT2A (0.33) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL6194787 | 0.84 | KMT2A (0.38) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL6200311 | 0.81 | KDM4E (0.45) | KDM4EALDH1A1KMT2AL3MBTL1AOC3 | |
| SCHEMBL8850313 | 0.80 | TBXA2R (0.40) | CYP2D6ALDH1A1NPSR1KMT2A | |
| SCHEMBL8851024 | 0.79 | TNF (0.46) | — | |
| SCHEMBL5075091 | 0.77 | KDM4E (0.41) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6995418 | 0.76 | KDM4E (0.40) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL6197600 | 0.74 | KDM4E (0.37) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL13759841 | 0.72 | KDM4E (0.44) | KDM4ETP53CYP2D6HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0768302-B1 | Hydroxypyridinones | NOVARTIS AG (CH) | 2005-07-06 | — | — | EP | disclosed |
| US-5688815-A | COMPOUNDS FOR REMOVAL OF EXCESS IRON IN MAMMALS | CIBA GEIGY CORPORATION (US) | 1997-11-18 | — | — | US | disclosed |