Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 3/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8850201 | 0.89 | FABP4 (0.40) | KMT2ACYP2D6PTGDR2FABP4FABP5 | |
| SCHEMBL8851069 | 0.88 | KDM4E (0.36) | TBXA2RKMT2ACYP2D6PTGDR2FABP4 | |
| SCHEMBL6194787 | 0.85 | KMT2A (0.38) | TBXA2RFFAR1KMT2ACYP2D6ALDH1A1 | |
| SCHEMBL8851024 | 0.85 | TNF (0.46) | LMNA | |
| SCHEMBL6196542 | 0.84 | KMT2A (0.33) | MAPK14KMT2ACYP2D6ALDH1A1NPSR1 | |
| SCHEMBL8850682 | 0.82 | CYP1A2 (0.40) | KMT2APTGDR2ALDH1A1FABP4FABP5 | |
| SCHEMBL8850489 | 0.80 | SMN1; SMN2 (0.49) | KMT2APTGDR2ALDH1A1NPSR1 | |
| SCHEMBL6198544 | 0.80 | KDM4E (0.35) | KMT2ACYP2D6ALDH1A1NPSR1 | |
| SCHEMBL27515247 | 0.76 | SMN1; SMN2 (0.48) | KMT2ACYP2D6PTGDR2ALDH1A1NPSR1 | |
| SCHEMBL6200311 | 0.75 | KDM4E (0.45) | KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688815-A | COMPOUNDS FOR REMOVAL OF EXCESS IRON IN MAMMALS | CIBA GEIGY CORPORATION (US) | 1997-11-18 | — | — | US | disclosed |