Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | UTS2R | Q9UKP6 | 8/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6195127 | 0.91 | SMN1; SMN2 (0.50) | KMT2AMEN1UTS2RUSP2LMNA | |
| SCHEMBL4864362 | 0.87 | CARM1 (0.49) | KMT2AMEN1UTS2RHTR2CADRA2A | |
| SCHEMBL6201249 | 0.87 | UTS2R (0.61) | KMT2AMEN1UTS2RUSP2LMNA | |
| SCHEMBL6195968 | 0.84 | KMT2A (0.53) | KMT2AMEN1UTS2RHTR2CADRA2A | |
| SCHEMBL5733134 | 0.81 | KMT2A (0.57) | KMT2AMEN1UTS2RUSP2LMNA | |
| SCHEMBL6196354 | 0.80 | DRD2 (0.53) | KMT2AMEN1UTS2RHTR2CADRA2A | |
| SCHEMBL5527306 | 0.80 | HRH3 (0.68) | KMT2AMEN1UTS2RHRH3HDAC8 | |
| SCHEMBL6198166 | 0.79 | CCR3 (0.60) | KMT2AMEN1UTS2RSLC6A2SLC6A4 | |
| SCHEMBL6199389 | 0.79 | UTS2R (0.60) | KMT2AMEN1UTS2RUSP2LMNA | |
| SCHEMBL6198960 | 0.79 | CCR3 (0.48) | UTS2RHTR2CADRA2ADRD2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499607-B1 | 4-(PIPERIDYL- AND PYRROLIDYL-ALKYL-UREIDO)-QUINOLINES AS UROTENSIN II RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2005-12-07 | — | — | EP | disclosed |