Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 18/20 | 0.72 |
| ▸ | KCNQ2 | O43526 | 18/20 | 0.72 |
| ▸ | KCNE1 | P15382 | 14/20 | 0.72 |
| ▸ | KCNQ1 | P51787 | 14/20 | 0.72 |
| ▸ | BACE1 | P56817 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5217440 | 0.84 | KCNQ3 (1.00) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL5217004 | 0.84 | KCNQ3 (1.00) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL5215207 | 0.83 | KCNQ3 (0.81) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL5217560 | 0.83 | KCNQ3 (0.79) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL5214418 | 0.83 | KCNQ3 (1.00) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL5213995 | 0.81 | KCNQ3 (0.77) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL5213999 | 0.81 | KCNQ3 (0.77) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL13947174 | 0.81 | RAB9A (0.83) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL14339874 | 0.79 | KCNQ3 (1.00) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL14339875 | 0.79 | KCNQ3 (1.00) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363884-A4 | PYRIDINE-SUBSTITUTED BENZANILIDES AS POTASSIUM ION CHANNEL OPENERS | ICAGEN INC (US) | 2005-03-30 | — | — | EP | disclosed |
| EP-1363884-A2 | PYRIDINE-SUBSTITUTED BENZANILIDES AS POTASSIUM ION CHANNEL OPENERS | Icagen, Inc. (US) | 2003-11-26 | — | — | EP | disclosed |
| EP-1208085-A4 | BENZANILIDES AS POTASSIUM CHANNEL OPENERS | ICAGEN INC (US) | 2003-05-02 | — | — | EP | disclosed |
| WO-2002062295-A2 | PYRIDINE-SUBSTITUTED BENZANILIDES AS POTASSIUM ION CHANNEL OPENERS | ICAGEN, INC. (US) | 2002-08-15 | — | — | WO | disclosed |
| EP-1208085-A2 | BENZANILIDES AS POTASSIUM CHANNEL OPENERS | Icagen, Inc. (US) | 2002-05-29 | — | — | EP | disclosed |
| WO-2001010380-A2 | BENZANILIDES AS POTASSIUM CHANNEL OPENERS | ICAGEN, INC. (US) | 2001-02-15 | — | — | WO | disclosed |