Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.80 |
| ▸ | CHKA | P35790 | 1/20 | 0.80 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | HBB | P68871 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL28113160 | 0.95 | CHRM5 (0.89) | CHRM5CHKAMAPTSMN1; SMN2KMT2A | |
| Pyridine SCHEMBL6553352 | 0.90 | CHKA (0.64) | CHRM5CHKAMAPTSMN1; SMN2KMT2A | |
| Pyridine SCHEMBL1830428 | 0.90 | CHRM5 (0.80) | CHRM5CHKAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL189 | 0.89 | — | — | |
| SCHEMBL8664726 | 0.89 | CHRM5 (1.00) | CHRM5CHKAMAPTSMN1; SMN2KMT2A | |
| Toluene SCHEMBL3335898 | 0.89 | CHRM5 (0.70) | CHRM5CHKAMAPTSMN1; SMN2KMT2A | |
| Phosphine SCHEMBL23270013 | 0.87 | CHRM5 (0.94) | CHRM5CHKAMAPTSMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL9013636 | 0.87 | CHRM5 (0.94) | CHRM5CHKAMAPTSMN1; SMN2KMT2A | |
| Bromide SCHEMBL393565 | 0.87 | CHRM5 (0.94) | CHRM5CHKAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL4405649 | 0.87 | CHRM5 (0.94) | CHRM5CHKAMAPTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1199306-B1 | BIARYLUREA DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2005-12-07 | — | — | EP | disclosed |
| EP-0504426-A1 | AROMATIC POLYESTER AND PRODUCTION THEREOF | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1992-09-23 | — | — | EP | disclosed |