Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 13/20 | 0.61 |
| ▸ | AGXT | P21549 | 5/20 | 0.58 |
| ▸ | TACR1 | P25103 | 2/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7226338 | 0.97 | IDO1 (0.63) | IDO1AGXT | |
| SCHEMBL14700068 | 0.84 | IDO1 (0.72) | IDO1AGXT | |
| SCHEMBL8516125 | 0.78 | TACR1 (0.52) | TACR1PARP10 | |
| SCHEMBL8728582 | 0.77 | IDO1 (0.50) | IDO1AGXT | |
| SCHEMBL402229 | 0.77 | IDO1 (1.00) | IDO1AGXT | |
| SCHEMBL1144911 | 0.76 | TACR1 (0.41) | IDO1TACR1PARP10 | |
| SCHEMBL15947362 | 0.75 | IDO1 (0.52) | IDO1AGXT | |
| Hydrochloric Acid SCHEMBL662679 | 0.75 | IDO1 (1.00) | IDO1AGXT | |
| SCHEMBL3154601 | 0.74 | AGXT (1.00) | IDO1AGXT | |
| SCHEMBL11313774 | 0.74 | PARP10 (0.47) | IDO1TACR1PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1266887-B1 | Indenoindoline derivatives, their process of preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2005-08-17 | — | — | EP | disclosed |
| EP-1266887-A2 | Indenoindoline derivatives, their process of preparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2002-12-18 | — | — | EP | disclosed |