Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4570823 | 0.77 | HPGD (0.36) | — | |
| SCHEMBL6199663 | 0.77 | IDO1 (0.61) | IDO1AGXT | |
| SCHEMBL8728579 | 0.75 | RAPGEF4 (0.30) | — | |
| Hydrochloric Acid SCHEMBL7226338 | 0.75 | IDO1 (0.63) | IDO1AGXT | |
| SCHEMBL13888666 | 0.71 | TACR1 (0.33) | — | |
| SCHEMBL91292 | 0.70 | LOXL2 (0.35) | — | |
| SCHEMBL16105713 | 0.69 | RAPGEF4 (0.43) | — | |
| SCHEMBL16105836 | 0.69 | SHBG (0.46) | — | |
| SCHEMBL26781740 | 0.69 | ALDH1A1 (0.53) | — | |
| SCHEMBL14700068 | 0.69 | IDO1 (0.72) | IDO1AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609058-B1 | Hexahydronaphthalene ester derivatives, their preparation and their therapeutic uses | SANKYO CO (JP) | 1998-12-09 | — | — | EP | disclosed |
| US-5491167-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY, LIMITED (JP) | 1996-02-13 | — | — | US | disclosed |
| EP-0609058-A2 | Hexahydronaphthalene ester derivatives, their preparation and their therapeutic uses | SANKYO COMPANY LIMITED (JP) | 1994-08-03 | — | — | EP | disclosed |