Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | RELA | Q04206 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.58 |
| ▸ | HTR2C | P28335 | 3/20 | 0.53 |
| ▸ | CNR1 | P21554 | 10/20 | 0.52 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | PNPLA2 | Q96AD5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6201643 | 0.89 | HTR2A (0.79) | HTR2AHTR2CCNR1CNR2 | |
| SCHEMBL6200786 | 0.87 | HTR2A (0.77) | HTR2ANPC1RAB9AMAPTMEN1 | |
| SCHEMBL6201386 | 0.86 | HTR2A (0.68) | HTR2AMAPTHTR2CCNR1CNR2 | |
| SCHEMBL6198676 | 0.85 | HTR2A (0.64) | HTR2AMAPTMEN1TP53KMT2A | |
| SCHEMBL6198462 | 0.84 | HTR2A (0.62) | HTR2AMAPTMEN1LMNATSHR | |
| SCHEMBL6196200 | 0.83 | HTR2A (0.65) | HTR2ANPC1RAB9AMAPTMEN1 | |
| SCHEMBL6195174 | 0.82 | HTR2A (0.60) | HTR2ANPC1RAB9AMAPTMEN1 | |
| SCHEMBL6200665 | 0.82 | HTR2A (0.57) | HTR2ANPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL6198156 | 0.81 | TRPV1 (0.62) | HTR2ANPC1RAB9AMAPTMEN1 | |
| SCHEMBL6199415 | 0.80 | HTR2A (0.64) | HTR2ANPC1RAB9AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509505-A2 | SMALL MOLECULE MODULATORS OF THE 5−HT2A SEROTONIN RECEPTOR USEFUL FOR THE PROPHYLAXIS AND TREATMENT OF DISORDERS RELATED THERETO | Arena Pharmaceuticals, Inc. (US) | 2005-03-02 | — | — | EP | claimed |
| WO-2003062206-A2 | SMALL MOLECULE MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE PROPHYLAXIS AND TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2003-07-31 | — | — | WO | claimed |