Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6199803 | 0.99 | SLC6A2 (0.41) | KMT2AMEN1SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL6201093 | 0.97 | SLC6A2 (0.41) | KMT2AMEN1SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL6199172 | 0.95 | SLC6A2 (0.42) | KMT2ASLC6A2SLC6A4CNR1 | |
| SCHEMBL6201331 | 0.94 | KMT2A (0.38) | KMT2AMEN1SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL6196495 | 0.93 | CYP3A4 (0.38) | KMT2AMEN1SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL6202589 | 0.91 | KMT2A (0.37) | KMT2AMEN1SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL6197826 | 0.89 | KMT2A (0.38) | KMT2AMEN1SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL6201334 | 0.85 | CCR5 (0.39) | KMT2AMEN1CCR5NPSR1CNR1 | |
| SCHEMBL6199632 | 0.84 | RECQL (0.47) | CCR5 | |
| SCHEMBL8118085 | 0.84 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1048658-B1 | ALICYCLIC ACYLATED HETEROCYCLIC DERIVATIVES | SANKYO CO (JP) | 2005-06-15 | — | — | EP | disclosed |
| US-6288059-B1 | ANTIASTHMATIC, ANTIALLERGEN AGENTS; URINARY INCONTINENCE; NATURAL KILLER CELL RECEPTOR AND TACHYKININ ANTAGONISTS | SANKYO COMPANY, LIMITED (JP) | 2001-09-11 | — | — | US | disclosed |
| CN-1284070-A | Alicyclic acylated heterocyclic derivatives | SANKYO CO (JP) | 2001-02-14 | — | — | CN | disclosed |
| EP-1048658-A1 | ALICYCLIC ACYLATED HETEROCYCLIC DERIVATIVES | Sankyo Company Limited (JP) | 2000-11-02 | — | — | EP | disclosed |