Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | VNN1 | O95497 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6196427 | 0.89 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPTALDH1A1LMNAEGLN1 | |
| SCHEMBL6202614 | 0.85 | EGLN1 (0.47) | LMNAEGLN1CNR2NR3C1HSP90AA1 | |
| SCHEMBL6766940 | 0.85 | EGLN1 (0.47) | SMN1; SMN2ALDH1A1LMNAEGLN1CNR2 | |
| SCHEMBL6199879 | 0.84 | KMT2A (0.46) | SMN1; SMN2MAPTALDH1A1LMNAEGLN1 | |
| SCHEMBL6201571 | 0.84 | SMN1; SMN2 (0.45) | SMN1; SMN2MAPTALDH1A1LMNAEGLN1 | |
| SCHEMBL6197287 | 0.82 | SMN1; SMN2 (0.55) | SMN1; SMN2MAPTALDH1A1LMNAEGLN1 | |
| SCHEMBL6198193 | 0.82 | EGLN1 (0.54) | SMN1; SMN2ALDH1A1LMNAEGLN1CNR2 | |
| SCHEMBL6195970 | 0.81 | EGLN1 (0.46) | SMN1; SMN2MAPTALDH1A1LMNAEGLN1 | |
| SCHEMBL6199108 | 0.81 | KMT2A (0.47) | SMN1; SMN2MAPTALDH1A1LMNAEGLN1 | |
| SCHEMBL6198962 | 0.81 | SMN1; SMN2 (0.55) | SMN1; SMN2MAPTALDH1A1LMNAEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | claimed |