Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6201955 | 0.91 | EGLN1 (0.42) | SMN1; SMN2EGLN1MEN1KMT2ACYP1A2 | |
| SCHEMBL6201118 | 0.86 | EGLN1 (0.44) | ALDH1A1EGLN1MEN1KMT2ALMNA | |
| SCHEMBL6196427 | 0.85 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPTALDH1A1EGLN1CNR2 | |
| SCHEMBL6201569 | 0.84 | KMT2A (0.46) | SMN1; SMN2MAPTALDH1A1EGLN1MEN1 | |
| SCHEMBL6200422 | 0.84 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPTALDH1A1EGLN1CNR2 | |
| SCHEMBL6203808 | 0.84 | EGLN1 (0.49) | SMN1; SMN2ALDH1A1EGLN1CNR2MEN1 | |
| SCHEMBL6199814 | 0.84 | P2RX1 (0.45) | MAPTEGLN1CNR2LMNA | |
| SCHEMBL6204166 | 0.83 | EGLN1 (0.43) | ALDH1A1EGLN1MEN1KMT2ALMNA | |
| SCHEMBL6201589 | 0.83 | EGLN1 (0.42) | ALDH1A1EGLN1MEN1KMT2ALMNA | |
| SCHEMBL6202644 | 0.82 | EGLN1 (0.42) | SMN1; SMN2MAPTALDH1A1EGLN1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | claimed |